Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4430146 | 0.84 | RNPEP (0.46) | ALDH1A1KDM4EL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL4430147 | 0.84 | RNPEP (0.46) | ALDH1A1KDM4EL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL14383421 | 0.79 | RNPEP (0.47) | ALDH1A1KDM4EL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL2106791 | 0.79 | RNPEP (0.47) | ALDH1A1KDM4EL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL2106793 | 0.79 | RNPEP (0.47) | ALDH1A1KDM4EL3MBTL1SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL8602261 | 0.77 | RNPEP (0.46) | ALDH1A1KDM4EL3MBTL1SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL8602262 | 0.77 | RNPEP (0.46) | ALDH1A1KDM4EL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL3869335 | 0.77 | LMNA (0.51) | ALDH1A1KDM4EL3MBTL1LMNARNPEP | |
| SCHEMBL14404929 | 0.77 | LMNA (0.51) | ALDH1A1KDM4EL3MBTL1LMNARNPEP | |
| SCHEMBL3869337 | 0.77 | LMNA (0.51) | ALDH1A1KDM4EL3MBTL1LMNARNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120093726-A1 | Radiolabeled Fluorine Derivatives of Methionine | CRC FOR BIOMEDICAL IMAGING DEVELOPMENT LTD. (AU) | 2012-04-19 | — | — | US | disclosed |
| EP-2411360-A1 | RADIOLABELED FLUORINE DERIVATIVES OF METHIONINE | CRC For Biomedical Imaging Development Ltd (AU) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010108210-A1 | RADIOLABELED FLUORINE DERIVATIVES OF METHIONINE | CRC FOR BIOMEDICAL IMAGING DEVELOPMENT LTD (AU) | 2010-09-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120093726-A1 | Radiolabeled Fluorine Derivatives of Methionine | BHMT2, MGMT, AHCY | ALDH1A1 1944/4885KDM4E 2789/4885L3MBTL1 1512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.