Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | VEGFA | P15692 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15956613 | 0.78 | ALDH1A1 (0.67) | TSHRALDH1A1MAPK1MAPTRAB9A | |
| SCHEMBL29133258 | 0.75 | ATM (0.47) | HPRT1TDP1PTGS2GCGRMAPK14 | |
| SCHEMBL9519907 | 0.71 | TSHR (0.39) | TSHRALDH1A1MAPK1HPRT1MAPT | |
| SCHEMBL4787759 | 0.70 | AHR (0.42) | TSHRRAB9ANPC1MEN1KMT2A | |
| SCHEMBL28812785 | 0.69 | PTGS2 (0.41) | ALDH1A1HPRT1MAPTNPC1POLB | |
| SCHEMBL28493859 | 0.69 | HPRT1 (0.50) | TSHRALDH1A1HPRT1RAB9AKMT2A | |
| SCHEMBL2551739 | 0.69 | MAPK1 (0.53) | TSHRALDH1A1MAPK1MAPTMEN1 | |
| SCHEMBL2493681 | 0.69 | ALDH1A1 (0.41) | TSHRALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL9733977 | 0.68 | HSD17B10 (0.58) | TSHRALDH1A1MAPK1MAPTRAB9A | |
| SCHEMBL29107305 | 0.68 | HPRT1 (0.49) | TSHRALDH1A1HPRT1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008122555-A1 | 2-NITRO-5-FLUORO-3',4'-DICHLOROBIPHENYL AND METHOD FOR THE PRODUCTION THEREOF | SALTIGO GMBH (DE) | 2008-10-16 | — | — | WO | claimed |