Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9812827 | 0.72 | ALOX5 (0.58) | TSHRALDH1A1ALOX5LMNASMN1; SMN2 | |
| SCHEMBL4749166 | 0.71 | TSHR (0.47) | TSHRALDH1A1HPRT1LMNASMN1; SMN2 | |
| SCHEMBL10975392 | 0.70 | HPRT1 (0.51) | TSHRALDH1A1HPRT1GRIN2DGRIN3B | |
| SCHEMBL29136385 | 0.68 | HPRT1 (0.49) | TSHRALDH1A1HPRT1GRIN2DGRIN3B | |
| SCHEMBL9337605 | 0.67 | MAPT (0.38) | TSHRALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL7607838 | 0.66 | TSHR (0.72) | TSHRALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL11589863 | 0.66 | TSHR (0.59) | TSHRALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL31451911 | 0.66 | ALDH1A1 (0.53) | TSHRALDH1A1ALOX5LMNASMN1; SMN2 | |
| SCHEMBL13982827 | 0.66 | MAPK1 (0.53) | TSHRALDH1A1LMNAMAPTP2RX1 | |
| SCHEMBL13982830 | 0.66 | MAPT (0.53) | TSHRALDH1A1LMNASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0312723-B1 | Method of and bait compositions for controlling mollusks | AMERICAN CYANAMID CO (US) | 1993-12-22 | — | — | EP | disclosed |