Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKACA | P17612 | 2/20 | 0.64 |
| ▸ | MARS1 | P56192 | 2/20 | 0.64 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.63 |
| ▸ | TARS1 | P26639 | 2/20 | 0.61 |
| ▸ | IARS1 | P41252 | 2/20 | 0.59 |
| ▸ | LARS1 | Q9P2J5 | 2/20 | 0.57 |
| ▸ | QARS1 | P47897 | 2/20 | 0.57 |
| ▸ | SARS1 | P49591 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.56 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2761284 | 0.82 | MARS1 (0.74) | PRKACAMARS1PLA2G2ATARS1ADORA3 | |
| SCHEMBL7757016 | 0.81 | MARS1 (0.73) | PRKACAMARS1TARS1IARS1LARS1 | |
| SCHEMBL8846496 | 0.81 | MARS1 (0.73) | PRKACAMARS1PLA2G2ATARS1LARS1 | |
| SCHEMBL16056094 | 0.80 | MARS1 (0.66) | PRKACAMARS1PLA2G2AADORA3ADORA2A | |
| SCHEMBL16057443 | 0.80 | MARS1 (0.66) | PRKACAMARS1PLA2G2AADORA3ADORA2A | |
| SCHEMBL2463542 | 0.79 | PRKACA (0.73) | PRKACAMARS1ADORA3ADORA2AADORA2B | |
| SCHEMBL9426538 | 0.79 | PRKACA (0.73) | PRKACAMARS1ADORA3ADORA2AADORA2B | |
| SCHEMBL6408983 | 0.79 | MARS1 (0.80) | PRKACAMARS1QARS1ADORA3ADORA2A | |
| SCHEMBL6408975 | 0.79 | MARS1 (0.80) | PRKACAMARS1QARS1ADORA3ADORA2A | |
| Alasa SCHEMBL21067643 | 0.79 | TARS1 (0.87) | MARS1TARS1IARS1LARS1SARS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124150-A1 | METHOD OF TREATING ENTERITIS, INTESTINAL DAMAGE, AND DIARRHEA FROM C. DIFFICILE WITH AN A2A ADENOSINE RECEPTOR AGONIST | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2008-10-16 | — | — | WO | disclosed |