Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15331973 | 0.71 | ACHE (0.53) | TYMP | |
| SCHEMBL15331802 | 0.71 | TYMP (0.48) | TYMPNPC1 | |
| SCHEMBL5154556 | 0.71 | NPC1 (0.55) | TYMPNPC1 | |
| SCHEMBL28448729 | 0.69 | TYMP (0.56) | TYMP | |
| SCHEMBL17524430 | 0.65 | TYMP (0.52) | TYMP | |
| SCHEMBL28441245 | 0.65 | TYMP (0.45) | TYMP | |
| SCHEMBL10826303 | 0.65 | TYMP (0.48) | TYMP | |
| SCHEMBL28433595 | 0.63 | MEN1 (0.32) | — | |
| SCHEMBL2884681 | 0.61 | TYMP (0.53) | TYMP | |
| SCHEMBL16751121 | 0.61 | KMT2A (0.42) | TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4567260-A | 6-CHLORO-5-FORMYL URACIL AND N-D-RIBITYL-=!O,4-XYLIDINE | TOYO JOZO KABUSHIKI KAISHA (JP) | 1986-01-28 | — | — | US | claimed |
| JP-59005186-A | — | — | None | — | — | JP | disclosed |
| US-10457682-B2 | Small molecules that bind MR1 | THE UNIVERSITY OF CHICAGO | 2019-10-29 | — | — | US | disclosed |
| EP-3274352-B1 | HETEROCYCLYLMETHYL-THIENOURACILE AS ANTAGONISTS OF THE ADENOSINE-A2B-RECEPTOR | Bayer Pharma AG (DE) | 2019-01-02 | — | — | EP | disclosed |
| EP-3274352-A1 | HETEROCYCLYLMETHYL-THIENOURACILE AS ANTAGONISTS OF THE ADENOSINE-A2B-RECEPTOR | Bayer Pharma Aktiengesellschaft (DE) | 2018-01-31 | — | — | EP | disclosed |
| WO-2016150901-A1 | HETEROCYCLYLMETHYL-THIENOURACILE AS ANTAGONISTS OF THE ADENOSINE-A2B-RECEPTOR | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-09-29 | — | — | WO | disclosed |
| US-8575178-B2 | Isothiazolo-pyrimidinedione derivatives as TRPA1 modulators | GLENMARK PHARMACEUTICALS S.A. (CH) | 2013-11-05 | — | — | US | disclosed |
| EP-2411397-B1 | ISOTHIAZOLO-PYRIMIDINEDIONE DERIVATIVES AS TRPA1 MODULATORS | GLENMARK PHARMACEUTICALS SA (CH) | 2013-05-29 | — | — | EP | disclosed |
| EP-2411397-A1 | ISOTHIAZOLO-PYRIMIDINEDIONE DERIVATIVES AS TRPA1 MODULATORS | Glenmark Pharmaceuticals S.A. (CH) | 2012-02-01 | — | — | EP | disclosed |
| US-20120010223-A1 | ISOTHIAZOLO-PYRIMIDINEDIONE DERIVATIVES AS TRPAI MODULATORS | GLENMARK PHARMACEUTICALS, S.A. (CH) | 2012-01-12 | — | — | US | disclosed |
| WO-2010109328-A1 | ISOTHIAZOLO-PYRIMIDINEDIONE DERIVATIVES AS TRPA1 MODULATORS | GLENMARK PHARMACEUTICALS, S.A. (CH) | 2010-09-30 | — | — | WO | disclosed |
| US-4567260-A | 6-CHLORO-5-FORMYL URACIL AND N-D-RIBITYL-=!O,4-XYLIDINE | TOYO JOZO KABUSHIKI KAISHA (JP) | 1986-01-28 | — | — | US | disclosed |
| US-4567260-A | 6-CHLORO-5-FORMYL URACIL AND N-D-RIBITYL-=!O,4-XYLIDINE | TOYO JOZO KABUSHIKI KAISHA (JP) | 1986-01-28 | — | — | US | disclosed |
| JP-S595186-A | NEW METHOD FOR 5-DEAZARIBOFLAVIN AND ITS INTERMEDIATE | TOYO JOZO CO LTD | 1984-01-12 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010223-A1 | ISOTHIAZOLO-PYRIMIDINEDIONE DERIVATIVES AS TRPAI MODULATORS | TRPA1, TRPV1, TRPC3 | TYMP 3034/4885NPC1 473/4885 |
| US-10457682-B2 | Small molecules that bind MR1 | MICA, HLA-DRB1, CD74 | TYMP 4808/4885NPC1 512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.