Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4750831 | 0.90 | FFAR4 (0.40) | FFAR4LMNAMAPTL3MBTL1ATM | |
| SCHEMBL4753360 | 0.88 | PTGDR2 (0.46) | FFAR4LMNAMAPTL3MBTL1ATM | |
| SCHEMBL4752820 | 0.85 | FFAR4 (0.51) | FFAR4KDM4EALDH1A1GAATP53 | |
| SCHEMBL219349 | 0.75 | ALDH1A1 (0.61) | MAPTL3MBTL1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL12674477 | 0.74 | CYP1A2 (0.56) | CYP1A2CYP2C9CYP2C19FFAR4LMNA | |
| Hydrochloric Acid SCHEMBL29156838 | 0.74 | MAPT (0.50) | CYP1A2CYP2C9CYP2C19LMNAMAPT | |
| SCHEMBL5277433 | 0.70 | KDM4E (0.56) | LMNAMAPTL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL22337091 | 0.70 | CYP1A2 (0.55) | CYP1A2CYP2C9CYP2C19LMNAMAPT | |
| SCHEMBL5278105 | 0.69 | PTGDR2 (0.52) | FFAR4LMNAL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL29950647 | 0.69 | CYP1A2 (0.55) | CYP1A2CYP2C9CYP2C19LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146063-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT6 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR Nyilvánosan Müködö Részvénytársagág (HU) | 2008-12-04 | — | — | WO | disclosed |