Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 6/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | HTR1B | P28222 | 2/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.42 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751044 | 0.85 | CYP1A2 (0.44) | FFAR4HTR6GAAKDM4EALDH1A1 | |
| SCHEMBL12969072 | 0.84 | HTR6 (0.58) | FFAR4HTR6HTR1AHTR1BHTR1D | |
| SCHEMBL4750831 | 0.82 | FFAR4 (0.40) | FFAR4HTR6KDM4EALDH1A1NR1I2 | |
| SCHEMBL4754004 | 0.82 | HTR6 (0.66) | FFAR4HTR6HTR1DHTR2CALDH1A1 | |
| SCHEMBL4753360 | 0.81 | PTGDR2 (0.46) | FFAR4KDM4EALDH1A1NR1I2 | |
| Hydrochloric Acid SCHEMBL966017 | 0.81 | HTR6 (0.65) | FFAR4HTR6HTR1AHTR1DHTR2C | |
| SCHEMBL2204461 | 0.78 | MAPT (0.58) | KDM4EALDH1A1TSHRHTR3EHTR3B | |
| SCHEMBL2200058 | 0.77 | HTR3E (0.68) | FFAR4HTR6GAAKDM4EALDH1A1 | |
| SCHEMBL6979317 | 0.77 | MAPT (0.54) | HTR6GAAKDM4EALDH1A1TSHR | |
| SCHEMBL19078400 | 0.75 | FFAR4 (0.58) | FFAR4HTR6HTR1AHTR1BHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146063-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT6 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR Nyilvánosan Müködö Részvénytársagág (HU) | 2008-12-04 | — | — | WO | disclosed |