Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | PPARD | Q03181 | 3/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | LIPC | P11150 | 1/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4750831 | 0.94 | FFAR4 (0.40) | PTGDR2PPARGPPARDPPARALIPC | |
| SCHEMBL4751044 | 0.88 | CYP1A2 (0.44) | DRD2DRD3ALDH1A1SMN1; SMN2FFAR4 | |
| SCHEMBL4752820 | 0.81 | FFAR4 (0.51) | NR1I2ALDH1A1FFAR4KDM4E | |
| SCHEMBL9579386 | 0.77 | DRD2 (0.58) | DRD2DRD3ALDH1A1L3MBTL1HSD17B10 | |
| SCHEMBL15473186 | 0.72 | PTGDR2 (0.52) | PTGDR2PPARGPPARDPPARAALDH1A1 | |
| SCHEMBL14029250 | 0.72 | PTGDR2 (0.52) | PTGDR2PPARGPPARDPPARAALDH1A1 | |
| SCHEMBL14028966 | 0.71 | PTGDR2 (0.51) | PTGDR2PPARGPPARDPPARAALDH1A1 | |
| SCHEMBL10352025 | 0.71 | L3MBTL1 (0.62) | PTGDR2PPARGPPARDPPARAALDH1A1 | |
| SCHEMBL17088080 | 0.70 | ALDH1A1 (0.52) | PTGDR2PPARGPPARDPPARANR1I2 | |
| SCHEMBL12968462 | 0.70 | PPARD (0.53) | PTGDR2PPARGPPARDPPARAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146063-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT6 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR Nyilvánosan Müködö Részvénytársagág (HU) | 2008-12-04 | — | — | WO | disclosed |