Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 11/20 | 0.58 |
| ▸ | HSD17B2 | P37059 | 10/20 | 0.58 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.44 |
| ▸ | FYN | P06241 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | ATP4A | P20648 | 1/20 | 0.42 |
| ▸ | ATP4B | P51164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8007463 | 0.84 | ESR1 (0.57) | HSD17B1HSD17B2SCN9ACYP3A4CYP2C9 | |
| SCHEMBL14564377 | 0.79 | SCN9A (0.62) | SCN9A | |
| SCHEMBL6202100 | 0.78 | SCN9A (0.56) | SCN9A | |
| SCHEMBL17794305 | 0.78 | SCN9A (0.53) | SCN9AMETAP2 | |
| SCHEMBL1354826 | 0.78 | SCN9A (0.53) | SCN9AMETAP2 | |
| SCHEMBL10263248 | 0.78 | SCN9A (0.53) | SCN9AMETAP2ATP4AATP4B | |
| SCHEMBL30370470 | 0.78 | SCN9A (0.53) | SCN9ACYP19A1 | |
| SCHEMBL6166963 | 0.77 | KMO (0.53) | SCN9A | |
| SCHEMBL16159336 | 0.76 | SCN9A (0.55) | HSD17B1HSD17B2SCN9ACYP3A4CYP2C9 | |
| SCHEMBL1186172 | 0.76 | ESR1 (0.46) | HSD17B1HSD17B2SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008129129-A1 | HETEROCYCLIC PHENYL CARBAMATES AS NOVEL FAAH-INHIBITORS | KUOPION YLIOPISTO (FI) | 2008-10-30 | — | — | WO | disclosed |
| WO-2008129129-A1 | HETEROCYCLIC PHENYL CARBAMATES AS NOVEL FAAH-INHIBITORS | KUOPION YLIOPISTO (FI) | 2008-10-30 | — | — | WO | disclosed |