Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751207 | 1.00 | RAB9A (0.60) | RAB9AGAAALDH1A1MAPTNPC1 | |
| SCHEMBL3018973 | 0.74 | LMNA (0.48) | RAB9AGAAALDH1A1MAPTNPC1 | |
| SCHEMBL3018977 | 0.74 | LMNA (0.48) | RAB9AGAAALDH1A1MAPTNPC1 | |
| SCHEMBL27986799 | 0.69 | RAB9A (0.60) | RAB9AGAAALDH1A1MAPTNPC1 | |
| SCHEMBL30521498 | 0.68 | IDO1 (0.52) | RAB9AGAAALDH1A1MAPTMEN1 | |
| SCHEMBL15063512 | 0.68 | PKM (0.80) | RAB9AGAAALDH1A1MAPTNPC1 | |
| SCHEMBL6169173 | 0.67 | MAPT (0.65) | RAB9AGAAALDH1A1MAPTNPC1 | |
| SCHEMBL9172490 | 0.66 | MAPT (0.45) | RAB9AALDH1A1MAPTNPC1MEN1 | |
| Silver SCHEMBL9172484 | 0.66 | MAPT (0.45) | RAB9AALDH1A1MAPTNPC1MEN1 | |
| SCHEMBL4016784 | 0.66 | ALDH1A1 (0.73) | RAB9AGAAALDH1A1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008144933-A1 | CINNAMOYL INHIBITORS OF TRANSGLUTAMINASE | Université de Montréal (CA) | 2008-12-04 | — | — | WO | disclosed |