Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4748849 | 0.77 | AR (0.43) | DPP4KCNH2 | |
| SCHEMBL4924063 | 0.69 | ALDH1A1 (0.36) | ALDH1A1KDM4ESMN1; SMN2DPP4KCNH2 | |
| SCHEMBL4733988 | 0.69 | KDM4E (0.40) | ALDH1A1KDM4ESMN1; SMN2DPP4KCNH2 | |
| SCHEMBL7098384 | 0.67 | ALDH1A1 (0.43) | ALDH1A1KDM4ESMN1; SMN2HPGD | |
| SCHEMBL1927578 | 0.67 | TDP1 (0.60) | ALDH1A1KDM4ESMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL8605901 | 0.66 | CHRNB4 (0.41) | ALDH1A1KDM4ESMN1; SMN2HPGDMEN1 | |
| SCHEMBL4751606 | 0.66 | PGR (0.44) | — | |
| SCHEMBL4731399 | 0.66 | ALDH1A1 (0.38) | ALDH1A1KDM4ESMN1; SMN2TSHRPOLB | |
| SCHEMBL147410 | 0.64 | KDM4E (0.41) | ALDH1A1KDM4EMAPTMAPK1HPGD | |
| SCHEMBL14022449 | 0.64 | NPC1 (0.47) | ALDH1A1KDM4ESMN1; SMN2DPP4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008135824-A1 | OXYALKYLPYRAZOLE COMPOUNDS USEFUL IN THERAPY | PFIZER LIMITED (GB) | 2008-11-13 | — | — | WO | disclosed |