Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.79 |
| ▸ | GAA | P10253 | 3/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.79 |
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | MTOR | P42345 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751703 | 1.00 | MAPT (0.79) | MAPTGAAKDM4ENPC1POLB | |
| SCHEMBL14938560 | 0.82 | MAPT (0.78) | MAPTGAAKDM4ENPC1POLB | |
| SCHEMBL10281920 | 0.79 | KDM4E (0.67) | MAPTGAAKDM4ENPC1RAB9A | |
| SCHEMBL17527524 | 0.79 | CTSL (0.70) | MAPTGAAKDM4EALDH1A1 | |
| SCHEMBL27177996 | 0.79 | MAPT (0.72) | MAPTGAAKDM4ENPC1POLB | |
| SCHEMBL5519818 | 0.79 | CTSL (0.70) | MAPTGAAKDM4EALDH1A1 | |
| SCHEMBL941204 | 0.79 | CTSL (0.70) | MAPTGAAKDM4EALDH1A1 | |
| SCHEMBL8740246 | 0.78 | KMT2A (0.81) | MAPTGAAKDM4EPOLBRAB9A | |
| SCHEMBL5809141 | 0.78 | GAA (0.65) | MAPTGAAKDM4ENPC1POLB | |
| SCHEMBL942323 | 0.74 | ALDH1A1 (0.70) | MAPTGAAKDM4EPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008129129-A1 | HETEROCYCLIC PHENYL CARBAMATES AS NOVEL FAAH-INHIBITORS | KUOPION YLIOPISTO (FI) | 2008-10-30 | — | — | WO | disclosed |