Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751767 | 1.00 | KDM2B (0.40) | KDM2BGRIN2CKMT2AALDH1A1MAPT | |
| SCHEMBL4780092 | 0.90 | KDM2B (0.43) | KDM2BKMT2AALDH1A1HTTDRD2 | |
| SCHEMBL4749046 | 0.89 | ALDH1A1 (0.34) | KMT2AALDH1A1MAPTKDM4ESLC6A4 | |
| SCHEMBL4749041 | 0.89 | ALDH1A1 (0.34) | KMT2AALDH1A1MAPTKDM4ESLC6A4 | |
| SCHEMBL4028033 | 0.86 | KDM2B (0.40) | KDM2BKMT2AALDH1A1HTTDRD4 | |
| SCHEMBL4022832 | 0.85 | KDM2B (0.43) | KDM2BKMT2ACCR3KDM4EHTT | |
| SCHEMBL4029178 | 0.85 | KDM2B (0.43) | KDM2BKMT2ACCR3KDM4EHTT | |
| SCHEMBL4024193 | 0.85 | KDM2B (0.43) | KDM2BKMT2ACCR3KDM4EHTT | |
| SCHEMBL4025347 | 0.84 | KIF11 (0.37) | ALDH1A1KDM4EDRD2DRD4 | |
| SCHEMBL13721664 | 0.84 | L3MBTL1 (0.43) | KDM2BKMT2AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | claimed |
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | disclosed |