SCHEMBL4752124

SCHEMBL4752124

CC(C)CC(Cc1ccccc1)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 1/20 0.50
MTNR1B P49286 1/20 0.50
SIGMAR1 Q99720 5/20 0.48
TAAR1 Q96RJ0 4/20 0.48
SLC6A2 P23975 3/20 0.48
SLC6A4 P31645 2/20 0.48
SLC6A3 Q01959 2/20 0.48
MAOA P21397 1/20 0.48
CYP2A6 P11509 1/20 0.48
ADORA2A P29274 1/20 0.48
ADORA1 P30542 1/20 0.48
SLC18A2 Q05940 1/20 0.45
CYP2D6 P10635 1/20 0.45
ADRB2 P07550 1/20 0.44
ADRB1 P08588 1/20 0.44
HTR1A P08908 1/20 0.44
ADORA3 P0DMS8 1/20 0.44
DRD2 P14416 1/20 0.44
ADRA2B P18089 1/20 0.44
ADRA2C P18825 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10589625 0.83 SLC6A2 (0.50) MTNR1AMTNR1BSIGMAR1TAAR1SLC6A2
SCHEMBL146771 0.82 MTNR1A (0.55) MTNR1AMTNR1BSIGMAR1TAAR1SLC6A2
SCHEMBL28696042 0.80 MTNR1A (0.53) MTNR1AMTNR1BSIGMAR1TAAR1SLC6A2
Hydrochloric Acid SCHEMBL30185866 0.80 MTNR1A (0.53) MTNR1AMTNR1BSIGMAR1TAAR1SLC6A2
SCHEMBL1760733 0.78 ESR1 (0.59) MTNR1AMTNR1BSIGMAR1TAAR1SLC6A2
SCHEMBL1774828 0.78 LMNA (0.46) TAAR1SLC6A3CYP2D6ADRA2BADRA1A
SCHEMBL11022593 0.77 MMP1 (0.37) CYP2D6
Hydrogen Peroxide SCHEMBL9456548 0.77 ESR1 (0.62) MTNR1AMTNR1BSIGMAR1TAAR1SLC6A2
Ammonia Solution, Strong SCHEMBL7275238 0.77 ESR1 (0.57) MTNR1AMTNR1BSIGMAR1TAAR1SLC6A2
SCHEMBL19090082 0.77 TAAR1 (0.56) TAAR1SLC6A2SLC6A4SLC6A3HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6967229-B2 Carbon-carbon initiators for use in golf balls ACUSHNET COMPANY (US) 2005-11-22 US claimed
US-20050009992-A1 Carbon-carbon initiators for use in golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-01-13 US claimed
CN-104281006-B Radiation-ray sensitive composition 三菱瓦斯化学株式会社 2019-01-22 CN disclosed
CN-108008600-A Radiation-ray sensitive composition 三菱瓦斯化学株式会社 2018-05-08 CN disclosed
US-9056227-B2 Golf ball comprising a core having a shallow hardness gradient ACUSHNET COMPANY (US) 2015-06-16 US disclosed
US-8968117-B2 Dual-core comprising zero gradient center and positive gradient outer core layer ACUSHNET COMPANY (US) 2015-03-03 US disclosed
US-20130109504-A1 DUAL-CORE COMPRISING ZERO GRADIENT CENTER AND POSITIVE GRADIENT OUTER CORE LAYER ACUSHNET COMPANY (US) 2013-05-02 US disclosed
US-20130109506-A1 GOLF BALL COMPRISING A CORE HAVING A SHALLOW HARDNESS GRADIENT ACUSHNET COMPANY (US) 2013-05-02 US disclosed
WO-2008141767-A2 COMPOSITE MATERIAL BASED ON VINYL AROMATIC POLYMERS HAVING ENHANCED THERMAL INSULATION PROPERTIES AND PROCESS FOR THE PREPARATION THEREOF POLIMERI EUROPA S.P.A. (IT) 2008-11-27 WO disclosed
US-6967229-B2 Carbon-carbon initiators for use in golf balls ACUSHNET COMPANY (US) 2005-11-22 US disclosed
US-20050009992-A1 Carbon-carbon initiators for use in golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-01-13 US disclosed
EP-0717098-B1 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON MITSUBISHI OIL CORP (JP) 2004-01-21 EP disclosed
US-5817251-A AROMATIC HYDROCARBON LUBRICANT NIPPON OIL CO., LTD. (JP) 1998-10-06 US disclosed
US-5711895-A Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group NIPPON OIL CO., LTD. (JP) 1998-01-27 US disclosed
EP-0717098-A2 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON OIL CO. LTD. (JP) 1996-06-19 EP disclosed
EP-0322669-B1 DRY LIQUID ANALYSIS ELEMENT FUJI PHOTO FILM CO., LTD. (JP) 1993-08-11 EP disclosed
US-5122451-A Easy permeation of high molecular weight component FUJI PHOTO FILM LTD. (JP) 1992-06-16 US disclosed
EP-0322669-A1 Dry liquid analysis element FUJI PHOTO FILM CO., LTD. (JP) 1989-07-05 EP disclosed