Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.50 |
| ▸ | PTPRB | P23467 | 1/20 | 0.50 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4753019 | 0.86 | ALDH1A1 (0.53) | RAB9ASMN1; SMN2NPC1POLBALDH1A1 | |
| SCHEMBL4749265 | 0.80 | ALDH1A1 (0.58) | RAB9ASMN1; SMN2NPC1POLBALDH1A1 | |
| SCHEMBL4736437 | 0.77 | KMT2A (0.81) | RAB9ASMN1; SMN2NPC1POLBALDH1A1 | |
| SCHEMBL5330760 | 0.77 | HCAR2 (0.72) | RAB9ASMN1; SMN2NPC1POLBPTPN2 | |
| SCHEMBL4736482 | 0.76 | SMN1; SMN2 (0.52) | RAB9ASMN1; SMN2NPC1POLBALDH1A1 | |
| SCHEMBL17826401 | 0.75 | RAB9A (0.53) | RAB9ASMN1; SMN2NPC1POLBALDH1A1 | |
| SCHEMBL4789026 | 0.75 | SMN1; SMN2 (0.51) | RAB9ASMN1; SMN2NPC1POLBALDH1A1 | |
| SCHEMBL4752214 | 0.75 | L3MBTL1 (0.66) | RAB9ASMN1; SMN2NPC1POLBALDH1A1 | |
| SCHEMBL4751453 | 0.74 | L3MBTL1 (0.64) | RAB9ASMN1; SMN2NPC1POLBALDH1A1 | |
| SCHEMBL4751921 | 0.74 | L3MBTL1 (0.54) | RAB9ASMN1; SMN2NPC1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140214-A1 | USE OF AMINOTHIOPHENE DERIVATIVE FOR PREVENTING OR TREATING ISCHEMIC DISEASES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-11-20 | — | — | WO | disclosed |