Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.72 |
| ▸ | RAB9A | P51151 | 4/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.51 |
| ▸ | PTPRB | P23467 | 1/20 | 0.51 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5296521 | 0.85 | NPC1 (0.77) | HCAR2RAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL5066827 | 0.85 | HCAR2 (0.83) | HCAR2RAB9ANPC1PTPN2PTPRB | |
| SCHEMBL5330080 | 0.81 | HCAR2 (0.72) | HCAR2RAB9ANPC1PTPN2PTPRB | |
| SCHEMBL13781546 | 0.79 | HCAR2 (0.62) | HCAR2RAB9ANPC1PTPN2PTPRB | |
| SCHEMBL10741084 | 0.77 | PTPN2 (0.62) | HCAR2RAB9ANPC1PTPN2PTPRB | |
| SCHEMBL5294571 | 0.77 | HCAR2 (0.71) | HCAR2RAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL4752200 | 0.77 | RAB9A (0.52) | RAB9ANPC1PTPN2PTPRBPTPN6 | |
| SCHEMBL5334252 | 0.77 | HCAR2 (0.49) | HCAR2POLBHDAC1HDAC6 | |
| SCHEMBL5300923 | 0.76 | HCAR2 (0.65) | HCAR2RAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL27521280 | 0.76 | HCAR2 (0.73) | HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007015744-A1 | DISUBSTITUTED THIENYL COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2007-02-08 | — | — | WO | disclosed |