Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 6/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.57 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.57 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4753018 | 0.84 | ALDH1A1 (0.80) | ALDH1A1MAPK1MAPTSMN1; SMN2HTT | |
| SCHEMBL4752207 | 0.84 | ALDH1A1 (0.80) | ALDH1A1MAPK1MAPTSMN1; SMN2HTT | |
| SCHEMBL5066789 | 0.82 | ALDH1A1 (0.76) | ALDH1A1MAPK1MAPTSMN1; SMN2HTT | |
| SCHEMBL4749266 | 0.81 | ALDH1A1 (0.73) | ALDH1A1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7377084 | 0.79 | ALDH1A1 (0.71) | ALDH1A1MAPK1MAPTSMN1; SMN2MAPK10 | |
| SCHEMBL5294918 | 0.74 | MAPK8 (0.68) | ALDH1A1MAPK1MAPTSMN1; SMN2HTT | |
| SCHEMBL7778609 | 0.74 | ALDH1A1 (0.66) | ALDH1A1MAPTSMN1; SMN2POLBKMT2A | |
| SCHEMBL4296967 | 0.74 | MAPT (0.82) | ALDH1A1MAPK1MAPTSMN1; SMN2POLB | |
| SCHEMBL7933290 | 0.73 | MAPK8 (0.66) | ALDH1A1MAPK1MAPTSMN1; SMN2HTT | |
| SCHEMBL4749588 | 0.73 | SMN1; SMN2 (0.67) | ALDH1A1MAPK1MAPTSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140214-A1 | USE OF AMINOTHIOPHENE DERIVATIVE FOR PREVENTING OR TREATING ISCHEMIC DISEASES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-11-20 | — | — | WO | claimed |
| WO-2008140214-A1 | USE OF AMINOTHIOPHENE DERIVATIVE FOR PREVENTING OR TREATING ISCHEMIC DISEASES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-11-20 | — | — | WO | disclosed |