Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.80 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.80 |
| ▸ | MAPT | P10636 | 4/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | HPGD | P15428 | 2/20 | 0.70 |
| ▸ | CASP3 | P42574 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | ATM | Q13315 | 1/20 | 0.70 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.70 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.70 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | MAPK10 | P53779 | 5/20 | 0.60 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.60 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4752207 | 0.88 | ALDH1A1 (0.80) | ALDH1A1MAPK1MAPTSMN1; SMN2LMNA | |
| SCHEMBL5066789 | 0.85 | ALDH1A1 (0.76) | ALDH1A1MAPK1MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL4752209 | 0.84 | ALDH1A1 (0.74) | ALDH1A1MAPK1MAPTSMN1; SMN2LMNA | |
| SCHEMBL5301897 | 0.81 | NPC1 (0.56) | ALDH1A1MAPK1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL5301746 | 0.80 | KMT2A (0.77) | ALDH1A1SMN1; SMN2LMNAHPGDCASP3 | |
| SCHEMBL4751454 | 0.80 | MAPK1 (0.51) | ALDH1A1MAPK1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL4751462 | 0.79 | NPSR1 (0.78) | ALDH1A1MAPTSMN1; SMN2LMNAHPGD | |
| SCHEMBL4749588 | 0.78 | SMN1; SMN2 (0.67) | ALDH1A1MAPK1MAPTSMN1; SMN2LMNA | |
| SCHEMBL4751448 | 0.77 | KMT2A (0.65) | ALDH1A1MAPTSMN1; SMN2LMNAHPGD | |
| SCHEMBL5294918 | 0.77 | MAPK8 (0.68) | ALDH1A1MAPK1MAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140214-A1 | USE OF AMINOTHIOPHENE DERIVATIVE FOR PREVENTING OR TREATING ISCHEMIC DISEASES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-11-20 | — | — | WO | claimed |
| WO-2008140214-A1 | USE OF AMINOTHIOPHENE DERIVATIVE FOR PREVENTING OR TREATING ISCHEMIC DISEASES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-11-20 | — | — | WO | disclosed |