Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GAPDH | P04406 | 1/20 | 0.42 |
| ▸ | PREP | P48147 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4787548 | 0.82 | PTGS2 (0.60) | PTGS2LMNAGAAMAPTKMT2A | |
| SCHEMBL4752018 | 0.82 | PTGS2 (0.49) | PTGS2LMNAMAPTKMT2ATDP1 | |
| SCHEMBL4752038 | 0.77 | PTGS2 (1.00) | PTGS2MAPTPOLBPREPALDH1A1 | |
| SCHEMBL9158246 | 0.70 | HSD17B10 (0.76) | PTGS2LMNAGAAMAPTKMT2A | |
| SCHEMBL329365 | 0.70 | HSD17B10 (0.76) | PTGS2LMNAGAAMAPTKMT2A | |
| SCHEMBL12195468 | 0.70 | HSD17B10 (0.59) | PTGS2LMNAGAAMAPTKMT2A | |
| SCHEMBL4960001 | 0.69 | LMNA (0.71) | PTGS2LMNAGAAMAPTKMT2A | |
| Water SCHEMBL9344643 | 0.68 | HSD17B10 (0.73) | PTGS2LMNAGAAMAPTKMT2A | |
| SCHEMBL269329 | 0.68 | LMNA (0.80) | LMNAGAAMAPTKMT2APOLB | |
| SCHEMBL8374456 | 0.67 | LMNA (0.59) | LMNAGAAMAPTKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140251-A2 | CYCLOOXYGENASE-2 INHIBITORS | UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) | 2008-11-20 | — | — | WO | disclosed |