Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4752350 | 0.82 | PTGS2 (0.63) | PTGS2SMN1; SMN2L3MBTL1KMT2AMEN1 | |
| SCHEMBL1487475 | 0.70 | MEN1 (0.63) | HTTSMN1; SMN2L3MBTL1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL27709030 | 0.69 | MEN1 (0.61) | HTTSMN1; SMN2L3MBTL1KMT2AMEN1 | |
| SCHEMBL3818831 | 0.67 | SMN1; SMN2 (1.00) | HTTSMN1; SMN2L3MBTL1KMT2AMEN1 | |
| SCHEMBL10593687 | 0.66 | MTNR1A (0.59) | HTTSMN1; SMN2L3MBTL1KMT2AMEN1 | |
| SCHEMBL6516221 | 0.66 | KMT2A (0.73) | HTTSMN1; SMN2L3MBTL1KMT2AMEN1 | |
| SCHEMBL8579105 | 0.66 | KMT2A (0.72) | HTTSMN1; SMN2L3MBTL1KMT2AMEN1 | |
| SCHEMBL861674 | 0.65 | SMN1; SMN2 (0.84) | HTTSMN1; SMN2L3MBTL1KMT2AMEN1 | |
| SCHEMBL14808444 | 0.64 | KMT2A (1.00) | HTTSMN1; SMN2L3MBTL1KMT2AMEN1 | |
| SCHEMBL171415 | 0.64 | SMN1; SMN2 (0.73) | HTTSMN1; SMN2L3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140251-A2 | CYCLOOXYGENASE-2 INHIBITORS | UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) | 2008-11-20 | — | — | WO | claimed |
| WO-2008140251-A2 | CYCLOOXYGENASE-2 INHIBITORS | UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) | 2008-11-20 | — | — | WO | disclosed |