Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.36 |
| ▸ | PRKCB | P05771 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | LYN | P07948 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.36 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4101940 | 0.81 | KIF11 (0.45) | KIF11TLR7PDPK1CCNB2PRKCB | |
| SCHEMBL4752600 | 0.81 | KIF11 (0.42) | KIF11TLR7PDPK1CCNB2PRKCB | |
| SCHEMBL4753081 | 0.79 | KIF11 (0.45) | KIF11TLR7MEN1KMT2ARXFP1 | |
| SCHEMBL4753092 | 0.79 | KIF11 (0.45) | KIF11TLR7MEN1KMT2AKDM4E | |
| SCHEMBL5248649 | 0.79 | KIF11 (0.45) | KIF11TLR7CYP3A4SIGMAR1 | |
| SCHEMBL5250049 | 0.76 | KIF11 (0.43) | KIF11NPSR1SIGMAR1 | |
| SCHEMBL4101670 | 0.72 | PDE4A (0.46) | TLR7RXFP1KDM4ENPSR1 | |
| SCHEMBL4750941 | 0.72 | TP53 (0.44) | — | |
| SCHEMBL4750935 | 0.70 | TP53 (0.48) | CYP3A4MEN1KMT2ARXFP1NPSR1 | |
| SCHEMBL5740657 | 0.70 | KIF11 (0.46) | KIF11TLR7MEN1KMT2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008147852-A1 | KINESIN INHIBITORS | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2008-12-04 | — | — | WO | disclosed |