Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 7/20 | 0.53 |
| ▸ | MMP2 | P08253 | 6/20 | 0.53 |
| ▸ | MMP3 | P08254 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MMP13 | P45452 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 2/20 | 0.37 |
| ▸ | GSK3A | P49840 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenobarbital SCHEMBL18825042 | 0.79 | MMP2 (0.80) | MMP9MMP2MMP3KMT2AMEN1 | |
| Phenobarbital SCHEMBL16583 | 0.79 | MMP2 (0.80) | MMP9MMP2MMP3KMT2AMEN1 | |
| Phenobarbital SCHEMBL2592325 | 0.79 | MMP2 (0.80) | MMP9MMP2MMP3KMT2AMEN1 | |
| Phenobarbital SCHEMBL28099657 | 0.79 | MMP2 (0.80) | MMP9MMP2MMP3KMT2AMEN1 | |
| Phenobarbital SCHEMBL11529160 | 0.78 | MMP9 (0.73) | MMP9MMP2MMP3KMT2AMEN1 | |
| Phenobarbital SCHEMBL1322895 | 0.78 | MMP2 (0.77) | MMP9MMP2MMP3KMT2AMEN1 | |
| Phenobarbital SCHEMBL352763 | 0.78 | MMP2 (0.77) | MMP9MMP2MMP3KMT2AMEN1 | |
| Phenobarbital SCHEMBL22032658 | 0.78 | MMP2 (0.77) | MMP9MMP2MMP3KMT2AMEN1 | |
| Phenobarbital SCHEMBL2120028 | 0.78 | MMP2 (0.77) | MMP9MMP2MMP3KMT2AMEN1 | |
| Phenobarbital SCHEMBL3475428 | 0.78 | MMP2 (0.77) | MMP9MMP2MMP3KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0517327-B1 | Immunoassay with labeled hapten analogues | JOHNSON & JOHNSON CLIN DIAG (US) | 2001-08-16 | — | — | EP | disclosed |
| US-5601994-A | Immunoassay with novel labeled drug hapten analogues | JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) | 1997-02-11 | — | — | US | disclosed |
| EP-0517327-A2 | Immunoassay with labeled hapten analogues | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1992-12-09 | — | — | EP | disclosed |