Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4750492 | 0.82 | LMNA (0.42) | ALDH1A1LMNAKMT2AMEN1GAA | |
| SCHEMBL4752997 | 0.81 | LMNA (0.41) | ALDH1A1LMNAKMT2AMEN1GAA | |
| Hydrochloric Acid SCHEMBL4753988 | 0.81 | LMNA (0.41) | ALDH1A1LMNAKMT2AMEN1GAA | |
| SCHEMBL4752457 | 0.77 | PKM (0.41) | ALDH1A1LMNAKMT2AGAA | |
| SCHEMBL23667966 | 0.74 | LMNA (0.46) | ALDH1A1LMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4045697 | 0.73 | LMNA (0.45) | ALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL6734438 | 0.73 | LMNA (0.45) | ALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL4049990 | 0.73 | LMNA (0.45) | ALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL4752981 | 0.73 | LMNA (0.45) | LMNAKMT2A | |
| SCHEMBL4787825 | 0.72 | MAPT (0.40) | ALDH1A1LMNAHTTSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146064-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT7 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR (HU) | 2008-12-04 | — | — | WO | disclosed |