Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23667966 | 0.84 | LMNA (0.46) | LMNAKMT2APOLBALDH1A1MAPT | |
| SCHEMBL4752981 | 0.83 | LMNA (0.45) | LMNAKMT2APOLB | |
| SCHEMBL6734438 | 0.83 | LMNA (0.45) | LMNAKMT2APOLBALDH1A1MAPT | |
| SCHEMBL4045697 | 0.83 | LMNA (0.45) | LMNAKMT2APOLBALDH1A1MAPT | |
| SCHEMBL28496894 | 0.80 | KMT2A (0.39) | LMNAKMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL4750492 | 0.80 | LMNA (0.42) | LMNAKMT2APOLBALDH1A1MAPT | |
| SCHEMBL4044524 | 0.80 | LMNA (0.42) | LMNAKMT2APOLBALDH1A1MAPT | |
| SCHEMBL4041920 | 0.80 | ALDH1A1 (0.44) | LMNAKMT2APOLBALDH1A1MAPT | |
| SCHEMBL4752997 | 0.79 | LMNA (0.41) | LMNAKMT2APOLBALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL4753988 | 0.79 | LMNA (0.41) | LMNAKMT2APOLBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7576224-B2 | Insecticidal (dihalopropenyl) phenylalkyl substituted dihydrobenzofuran and dihydrobenzopyran derivatives | FMC CORPORATION (US) | 2009-08-18 | — | — | US | disclosed |
| US-7576224-B2 | Insecticidal (dihalopropenyl) phenylalkyl substituted dihydrobenzofuran and dihydrobenzopyran derivatives | FMC CORPORATION (US) | 2009-08-18 | — | — | US | disclosed |
| US-7576224-B2 | Insecticidal (dihalopropenyl) phenylalkyl substituted dihydrobenzofuran and dihydrobenzopyran derivatives | FMC CORPORATION (US) | 2009-08-18 | — | — | US | disclosed |
| EP-1620421-B1 | INSECTICIDAL (DIHALOPROPENYL) PHENYLALKYL SUBSTITUTED DIHYDROBENZOFURAN AND DIHYDROBENZOPYRAN DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2009-06-24 | — | — | EP | disclosed |
| EP-1620421-A4 | INSECTICIDAL (DIHALOPROPENYL) PHENYLALKYL SUBSTITUTED DIHYDROBENZOFURAN AND DIHYDROBENZOPYRAN DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2007-10-31 | — | — | EP | disclosed |
| US-20060094776-A1 | Insecticidal (dihalopropenyl) phenylalkyl substituted dihydrobenzofuran and dihydrobenzopyran derivatives | FMC CORPORATION | 2006-05-04 | — | — | US | disclosed |
| EP-1620421-A2 | INSECTICIDAL (DIHALOPROPENYL) PHENYLALKYL SUBSTITUTED DIHYDROBENZOFURAN AND DIHYDROBENZOPYRAN DERIVATIVES | FMC CORPORATION (US) | 2006-02-01 | — | — | EP | disclosed |
| US-6987194-B2 | Insecticidal (dihalopropenyl) phenylalkyl substituted dihydrobenzofuran and dihydrobenzopyran derivatives | FMC CORPORATION (US) | 2006-01-17 | — | — | US | disclosed |
| WO-2004098283-A2 | INSECTICIDAL (DIHALOPROPENYL) PHENYLALKYL SUBSTITUTED DIHYDROBENZOFURAN AND DIHYDROBENZOPYRAN DERIVATIVES | FMC CORPORATION (US) | 2004-11-18 | — | — | WO | disclosed |
| US-20040224994-A1 | Insecticidal (dihalopropenyl) phenylalkyl substituted dihydrobenzofuran and dihydrobenzopyran derivatives | FMC CORPORATION | 2004-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040224994-A1 | Insecticidal (dihalopropenyl) phenylalkyl substituted dihydrobenzofuran and dihydrobenzopyran derivatives | DDT, DHCR24, RPS24 | LMNA 4436/4885KMT2A 1467/4885POLB 4305/4885 |
| US-20060094776-A1 | Insecticidal (dihalopropenyl) phenylalkyl substituted dihydrobenzofuran and dihydrobenzopyran derivatives | DDT, DHCR24, L3MBTL1 | LMNA 4255/4885KMT2A 1363/4885POLB 4586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.