Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4750492 | 0.88 | LMNA (0.42) | LMNAKMT2AGAAMEN1POLB | |
| Hydrochloric Acid SCHEMBL4753988 | 0.87 | LMNA (0.41) | LMNAKMT2AGAAMEN1POLB | |
| SCHEMBL4752981 | 0.81 | LMNA (0.45) | LMNAKMT2APOLB | |
| SCHEMBL4753002 | 0.81 | ALDH1A1 (0.42) | LMNAKMT2AGAAMEN1ALDH1A1 | |
| SCHEMBL23667966 | 0.80 | LMNA (0.46) | LMNAKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL6734438 | 0.79 | LMNA (0.45) | LMNAKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL4049990 | 0.79 | LMNA (0.45) | LMNAKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL4045697 | 0.79 | LMNA (0.45) | LMNAKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL4044524 | 0.75 | LMNA (0.42) | LMNAKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL4041920 | 0.75 | ALDH1A1 (0.44) | LMNAKMT2APOLBALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146064-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT7 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR (HU) | 2008-12-04 | — | — | WO | disclosed |