Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751819 | 0.86 | NPC1 (0.56) | KDM4ETDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL4752214 | 0.86 | L3MBTL1 (0.66) | KDM4EL3MBTL1MEN1KMT2AMAPK1 | |
| SCHEMBL4749674 | 0.84 | NPSR1 (0.67) | TDP1MEN1KMT2AMAPTMAPK8 | |
| SCHEMBL4751921 | 0.80 | L3MBTL1 (0.54) | KDM4EL3MBTL1MEN1KMT2ANPC1 | |
| SCHEMBL4751453 | 0.80 | L3MBTL1 (0.64) | KDM4EL3MBTL1MEN1KMT2AMAPK1 | |
| SCHEMBL4752199 | 0.79 | SMN1; SMN2 (0.51) | KDM4ETDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL4753019 | 0.79 | ALDH1A1 (0.53) | L3MBTL1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL7461318 | 0.78 | L3MBTL1 (0.58) | KDM4EL3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL14743322 | 0.77 | NPC1 (0.67) | L3MBTL1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4752222 | 0.77 | SMN1; SMN2 (0.56) | KDM4ETDP1L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140214-A1 | USE OF AMINOTHIOPHENE DERIVATIVE FOR PREVENTING OR TREATING ISCHEMIC DISEASES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-11-20 | — | — | WO | claimed |
| WO-2008140214-A1 | USE OF AMINOTHIOPHENE DERIVATIVE FOR PREVENTING OR TREATING ISCHEMIC DISEASES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-11-20 | — | — | WO | disclosed |