Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4752214 | 0.83 | L3MBTL1 (0.66) | SMN1; SMN2HSD17B10ALDH1A1TSHRNPC1 | |
| SCHEMBL4753007 | 0.82 | LMNA (0.77) | SMN1; SMN2ALDH1A1LMNAMAPK8CYP1A2 | |
| SCHEMBL4751819 | 0.78 | NPC1 (0.56) | SMN1; SMN2ALDH1A1NPC1RAB9ATP53 | |
| SCHEMBL4752208 | 0.78 | LMNA (0.69) | SMN1; SMN2HSD17B10ALDH1A1TSHRNPC1 | |
| SCHEMBL4753022 | 0.77 | KDM4E (0.63) | SMN1; SMN2HSD17B10ALDH1A1TSHRNPC1 | |
| SCHEMBL4751921 | 0.77 | L3MBTL1 (0.54) | SMN1; SMN2HSD17B10ALDH1A1TSHRNPC1 | |
| SCHEMBL4751453 | 0.77 | L3MBTL1 (0.64) | SMN1; SMN2HSD17B10ALDH1A1TSHRNPC1 | |
| SCHEMBL4752199 | 0.76 | SMN1; SMN2 (0.51) | SMN1; SMN2HSD17B10ALDH1A1TSHRNPC1 | |
| SCHEMBL4753019 | 0.76 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1NPC1RAB9ACYP1A2 | |
| SCHEMBL11869892 | 0.74 | MTNR1A (0.55) | SMN1; SMN2HSD17B10ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140214-A1 | USE OF AMINOTHIOPHENE DERIVATIVE FOR PREVENTING OR TREATING ISCHEMIC DISEASES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-11-20 | — | — | WO | claimed |
| WO-2008140214-A1 | USE OF AMINOTHIOPHENE DERIVATIVE FOR PREVENTING OR TREATING ISCHEMIC DISEASES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-11-20 | — | — | WO | disclosed |