Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17826649 | 0.88 | POLB (0.48) | SMN1; SMN2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL4752214 | 0.87 | L3MBTL1 (0.66) | SMN1; SMN2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL4751921 | 0.86 | L3MBTL1 (0.54) | SMN1; SMN2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL4751453 | 0.86 | L3MBTL1 (0.64) | SMN1; SMN2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL4751819 | 0.85 | NPC1 (0.56) | SMN1; SMN2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL4753019 | 0.85 | ALDH1A1 (0.53) | SMN1; SMN2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL4749282 | 0.81 | ALDH1A1 (0.74) | SMN1; SMN2ALDH1A1HSD17B10LMNAPKM | |
| SCHEMBL4752208 | 0.80 | LMNA (0.69) | SMN1; SMN2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL4753022 | 0.79 | KDM4E (0.63) | SMN1; SMN2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL14095084 | 0.78 | KDM4E (0.74) | SMN1; SMN2KMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140214-A1 | USE OF AMINOTHIOPHENE DERIVATIVE FOR PREVENTING OR TREATING ISCHEMIC DISEASES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-11-20 | — | — | WO | claimed |
| US-9364468-B2 | Pharmaceutical composition for preventing or treating tuberculosis | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2016-06-14 | — | — | US | disclosed |
| US-9364468-B2 | Pharmaceutical composition for preventing or treating tuberculosis | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2016-06-14 | — | — | US | disclosed |
| US-20150133503-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING TUBERCULOSIS | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2015-05-14 | — | — | US | disclosed |
| US-20150133503-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING TUBERCULOSIS | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2015-05-14 | — | — | US | disclosed |
| WO-2008140214-A1 | USE OF AMINOTHIOPHENE DERIVATIVE FOR PREVENTING OR TREATING ISCHEMIC DISEASES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-11-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150133503-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING TUBERCULOSIS | GCDH, DHODH, MDH1 | SMN1; SMN2 3953/4885KMT2A 4831/4885MEN1 3716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.