SCHEMBL662008

SCHEMBL662008

Cc1cc(C)c(F)c(C)c1

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 11/20 0.46
ALDH1A1 P00352 3/20 0.38
KDM4E B2RXH2 1/20 0.38
LMNA P02545 1/20 0.38
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.38
TSHR P16473 1/20 0.37
CYP1A2 P05177 1/20 0.36
CYP2A6 P11509 1/20 0.36
FFAR4 Q5NUL3 1/20 0.35
ACHE P22303 3/20 0.35
TP53 P04637 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7025202 1.00 RAPGEF4 (0.46) RAPGEF4ALDH1A1KDM4ELMNAGAA
SCHEMBL8268053 0.84 RAPGEF4 (0.52) RAPGEF4ALDH1A1KDM4ELMNAGAA
SCHEMBL17471814 0.84 RAPGEF4 (0.38) RAPGEF4ALDH1A1MAPTTSHRACHE
SCHEMBL8761590 0.82 ACHE (0.52) RAPGEF4ALDH1A1KDM4ELMNAMAPT
SCHEMBL25162025 0.80 ALDH1A1 (0.52) RAPGEF4ALDH1A1KDM4ELMNAGAA
SCHEMBL8840849 0.80 RAPGEF4 (0.39) RAPGEF4ALDH1A1KDM4ELMNAGAA
SCHEMBL13550105 0.80 RAPGEF4 (0.41) RAPGEF4ALDH1A1LMNAMAPTTSHR
SCHEMBL8761509 0.80 SELL (0.50) RAPGEF4ALDH1A1KDM4ELMNAGAA
SCHEMBL17922617 0.80 RAPGEF4 (0.39) RAPGEF4ALDH1A1KDM4ELMNAGAA
SCHEMBL30695920 0.80 ALDH1A1 (0.52) RAPGEF4ALDH1A1KDM4ELMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120192204-A Preparation method of fluoro aromatic hydrocarbon compound 阜新孚隆宝医药科技有限公司 2025-06-24 CN claimed
CN-119219455-A Aromatic ring hydrogen-deuterium exchange reaction catalytic system and preparation method of deuterated aromatic hydrocarbon 国科大杭州高等研究院 2024-12-31 CN claimed
CN-120192204-A Preparation method of fluoro aromatic hydrocarbon compound 阜新孚隆宝医药科技有限公司 2025-06-24 CN disclosed
US-20250144020-A1 ULTRA-LONG FLOATING HYDROGEL RAFT FOR PROLONGED GASTRIC RETENTION AND APPLICATIONS REQUIRING BUOYANCY WITH CONTROLLED-RELEASE NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2025-05-08 US disclosed
US-12275640-B2 Method for manufacturing graphene Paragraph Limited (GB) 2025-04-15 US disclosed
CN-119219455-A Aromatic ring hydrogen-deuterium exchange reaction catalytic system and preparation method of deuterated aromatic hydrocarbon 国科大杭州高等研究院 2024-12-31 CN disclosed
CN-118515595-A Deep blue fluorescent molecule based on 2,2' -bisindole skeleton and preparation method and application thereof 泰州学院 2024-08-20 CN disclosed
US-11844267-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-12-12 US disclosed
US-11844267-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-12-12 US disclosed
WO-2023158377-A2 ULTRA-LONG FLOATING HYDROGEL RAFT FOR PROLONGED GASTRIC RETENTION & APPLICATIONS REQUIRING BUOYANCY WITH CONTROLLED-RELEASE NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2023-08-24 WO disclosed
EP-3489569-B1 GAS SUPPLY APPARATUS AND GAS SUPPLY METHOD SHOWA DENKO KK (JP) 2023-01-18 EP disclosed
US-5709968-A Non-aqueous electrolyte secondary battery SONY CORPORATION (JP) 1998-01-20 US disclosed
WO-1997041083-A1 PROCESS FOR THE PREPARATION OF FLUORO COMPOUNDS FROM THE CORRESPONDING AMINES RHODIA LIMITED (GB) 1997-11-06 WO disclosed
EP-0590259-B1 Process for the preparation of halogenated aromatic compounds BAYER AG (DE) 1997-10-29 EP disclosed
EP-0746050-A1 Non-aqueous electrolyte secondary battery SONY CORPORATION (JP) 1996-12-04 EP disclosed
US-5306849-A Process for the preparation of halogenated aromatics BAYER AKTIENGESELLSCHAFT (DE) 1994-04-26 US disclosed
EP-0590259-A2 Process for the preparation of halogenated aromatic compounds BAYER AG (DE) 1994-04-06 EP disclosed
US-4745235-A DECOMPOSITION BY DECARBOXYLATION IN PRESENCE OF ALUMINA IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-05-17 US disclosed
EP-0118241-B1 FLUORINATION PROCESS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-10-21 EP disclosed
EP-0118241-A1 Fluorination process IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-09-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11844267-B2 Organic electroluminescent materials and devices L1CAM, LEF1, EPCAM RAPGEF4 1098/4885ALDH1A1 330/4885KDM4E 3774/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.