Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.39 |
| ▸ | BCL9 | O00512 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4754617 | 0.80 | SMN1; SMN2 (0.46) | L3MBTL1HTR2ASMN1; SMN2MAPTKMT2A | |
| SCHEMBL2993617 | 0.77 | L3MBTL1 (0.41) | L3MBTL1HTR2ASMN1; SMN2MAPTKMT2A | |
| SCHEMBL6820153 | 0.76 | MAPT (0.49) | HTR2ASMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL6397367 | 0.76 | HTR2A (0.49) | L3MBTL1HTR2ASMN1; SMN2MAPTKMT2A | |
| SCHEMBL6820152 | 0.75 | HTR2A (0.51) | L3MBTL1HTR2ASMN1; SMN2MAPTKMT2A | |
| SCHEMBL5017678 | 0.75 | HTR2A (0.50) | HTR2ASMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL4753079 | 0.72 | HTR2A (0.42) | L3MBTL1HTR2ASMN1; SMN2MAPTKMT2A | |
| SCHEMBL29550444 | 0.72 | HTR2A (0.50) | HTR2ASMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL2162724 | 0.72 | CTSS (0.48) | MAPTCYP1A2CYP2D6ALDH1A1 | |
| SCHEMBL2162730 | 0.72 | CTSS (0.48) | MAPTCYP1A2CYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156832-A2 | RENIN INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2008-12-24 | — | — | WO | disclosed |