Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 10/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4750821 | 0.84 | ALDH1A1 (0.39) | HTR2AALDH1A1GLATP53CYP3A4 | |
| SCHEMBL18649397 | 0.82 | HTR2A (0.49) | HTR2AFFAR4ALDH1A1KMT2A | |
| SCHEMBL6734151 | 0.80 | ALDH1A1 (0.40) | ALDH1A1GLASMN1; SMN2NPC1KMT2A | |
| SCHEMBL4752959 | 0.80 | HTR2A (0.47) | HTR2AFFAR4ALDH1A1NPC1 | |
| SCHEMBL4753140 | 0.79 | ALDH1A1 (0.36) | HTR2AALDH1A1GLANPC1KMT2A | |
| SCHEMBL6311312 | 0.78 | ALDH1A1 (0.55) | ALDH1A1GLASMN1; SMN2NPC1KMT2A | |
| SCHEMBL17523384 | 0.78 | HTR2A (0.49) | HTR2AFFAR4ALDH1A1KMT2A | |
| SCHEMBL6311316 | 0.78 | ALDH1A1 (0.55) | ALDH1A1GLASMN1; SMN2NPC1KMT2A | |
| SCHEMBL16111361 | 0.73 | FFAR4 (0.47) | HTR2AFFAR4ALDH1A1TSHRKMT2A | |
| SCHEMBL18768202 | 0.72 | HTR2A (0.52) | HTR2AFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146064-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT7 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR (HU) | 2008-12-04 | — | — | WO | disclosed |