Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | PHLPP1 | O60346 | 1/20 | 0.33 |
| ▸ | ILK | Q13418 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4750506 | 0.81 | AKT1 (0.36) | ALDH1A1LMNAGAAMEN1KMT2A | |
| SCHEMBL4750821 | 0.79 | ALDH1A1 (0.39) | ALDH1A1LMNAGLAMEN1KMT2A | |
| SCHEMBL4753146 | 0.79 | HTR2A (0.47) | ALDH1A1GLAKMT2AHTR2ANPC1 | |
| SCHEMBL6734151 | 0.78 | ALDH1A1 (0.40) | ALDH1A1PKMLMNAGAAGLA | |
| SCHEMBL6311316 | 0.74 | ALDH1A1 (0.55) | ALDH1A1LMNAGLAMEN1KMT2A | |
| SCHEMBL6311312 | 0.74 | ALDH1A1 (0.55) | ALDH1A1LMNAGLAMEN1KMT2A | |
| SCHEMBL4787216 | 0.73 | AKT1 (0.38) | ALDH1A1LMNAAKT1HTR2APDPK1 | |
| SCHEMBL4750809 | 0.69 | DRD2 (0.44) | ALDH1A1LMNAHTR2AKDM4E | |
| SCHEMBL10805819 | 0.69 | LMNA (0.36) | ALDH1A1PKMLMNAGAAMEN1 | |
| SCHEMBL4789318 | 0.68 | AKT1 (0.34) | AKT1PDPK1PHLPP1ILK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146064-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT7 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR (HU) | 2008-12-04 | — | — | WO | disclosed |