Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | TLR3 | O15455 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751068 | 0.83 | ALDH1A1 (0.41) | ALDH1A1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL4750825 | 0.82 | ALDH1A1 (0.40) | ALDH1A1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL4753368 | 0.81 | ALDH1A1 (0.45) | ALDH1A1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL4751070 | 0.81 | ALDH1A1 (0.41) | ALDH1A1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL4750821 | 0.80 | ALDH1A1 (0.39) | ALDH1A1LMNASMN1; SMN2GLANPC1 | |
| SCHEMBL4753146 | 0.80 | HTR2A (0.47) | ALDH1A1SMN1; SMN2GLANPC1KMT2A | |
| SCHEMBL4751039 | 0.80 | ALDH1A1 (0.45) | ALDH1A1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL4750822 | 0.79 | CHRNB2 (0.44) | ALDH1A1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL4753173 | 0.78 | MAPT (0.41) | ALDH1A1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL4753140 | 0.78 | ALDH1A1 (0.36) | ALDH1A1LMNAGLANPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040186170-A1 | Benzofuran derivatives, pharmaceutical composition containing the same, and a process for the preparation of the active ingredient | EGIS GYOGYSZERGYAR (HU) | 2004-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040186170-A1 | Benzofuran derivatives, pharmaceutical composition containing the same, and a process for the preparation of the active ingredient | CYP2F1, CYP3A4, CYP2S1 | ALDH1A1 81/4885LMNA 2499/4885SMN1; SMN2 3211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.