Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QTRT1 | Q9BXR0 | 1/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | DHFR | P00374 | 3/20 | 0.49 |
| ▸ | TYMS | P04818 | 10/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | FABP6 | P51161 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4753487 | 0.84 | TNKS (0.51) | QTRT1MAPK14KDM4EDHFRTYMS | |
| SCHEMBL30864305 | 0.81 | TDP1 (0.67) | KDM4ERECQLTYMSHSP90AA1ESR2 | |
| SCHEMBL13984109 | 0.81 | QTRT1 (0.52) | QTRT1MAPK14KDM4EDHFRTYMS | |
| SCHEMBL4755403 | 0.80 | TYMS (0.72) | QTRT1TYMSPARP1 | |
| SCHEMBL1261208 | 0.80 | ABL1 (0.72) | ABL1FABP6HSP90AA1ESR2TDP1 | |
| SCHEMBL30249625 | 0.80 | TYMS (0.71) | QTRT1TYMSPARP1 | |
| SCHEMBL4311562 | 0.80 | TYMS (0.71) | QTRT1TYMSPARP1 | |
| SCHEMBL409345 | 0.79 | DHFR (0.60) | DHFRTYMS | |
| Hydrochloric Acid SCHEMBL4682535 | 0.79 | ABL1 (0.70) | ABL1FABP6HSP90AA1ESR2TDP1 | |
| SCHEMBL11375410 | 0.78 | GUSB (0.49) | KDM4ERECQLTDP1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008152142-A1 | 2 -AMINOQUINAZOLINE DERIVATIVES AND THEIR THERAPEUTIC USES | SOFTCURE PHARMACEUTICALS AB (SE) | 2008-12-18 | — | — | WO | disclosed |
| WO-2008152142-A1 | 2 -AMINOQUINAZOLINE DERIVATIVES AND THEIR THERAPEUTIC USES | SOFTCURE PHARMACEUTICALS AB (SE) | 2008-12-18 | — | — | WO | disclosed |