Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 3/20 | 0.49 |
| ▸ | QTRT1 | Q9BXR0 | 1/20 | 0.49 |
| ▸ | TYMS | P04818 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | DHFR | P00374 | 4/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | FPGS | Q05932 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2117452 | 0.89 | KDM4E (0.54) | TNKSKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4753152 | 0.84 | QTRT1 (0.56) | KDM4EMAPK14PARP1QTRT1TYMS | |
| SCHEMBL13984109 | 0.83 | QTRT1 (0.52) | KDM4EALDH1A1HPGDHSD17B10MAPK14 | |
| SCHEMBL4682076 | 0.81 | ALDH1A1 (0.64) | KDM4EALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL4755097 | 0.81 | TYMS (0.44) | KDM4EALDH1A1HPGDHSD17B10MAPK14 | |
| SCHEMBL30097387 | 0.81 | DHFR (0.59) | TYMSDHFR | |
| SCHEMBL6373153 | 0.80 | KDM4E (0.76) | TNKSKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4753842 | 0.80 | TYMS (0.44) | KDM4EALDH1A1HPGDHSD17B10MAPK14 | |
| SCHEMBL4753204 | 0.80 | TYMS (0.50) | KDM4EALDH1A1HPGDHSD17B10MAPK14 | |
| SCHEMBL8873503 | 0.79 | DHFR (0.46) | TNKSTYMSDHFRFPGS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108358856-B | It is a kind of prevent and treat peptic ulcer drug with and its preparation method and application | 牡丹江医学院 | 2019-09-13 | — | — | CN | disclosed |
| CN-108358856-A | It is a kind of prevention peptic ulcer drug with and its preparation method and application | 牡丹江医学院 | 2018-08-03 | — | — | CN | disclosed |
| WO-2008152142-A1 | 2 -AMINOQUINAZOLINE DERIVATIVES AND THEIR THERAPEUTIC USES | SOFTCURE PHARMACEUTICALS AB (SE) | 2008-12-18 | — | — | WO | disclosed |
| WO-2008152142-A1 | 2 -AMINOQUINAZOLINE DERIVATIVES AND THEIR THERAPEUTIC USES | SOFTCURE PHARMACEUTICALS AB (SE) | 2008-12-18 | — | — | WO | disclosed |