Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | FOLR1 | P15328 | 6/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.37 |
| ▸ | HRH2 | P25021 | 4/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | MLNR | O43193 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL276744 | 0.97 | HTR1A (0.46) | HTR1AFOLR1PTPN1MMP2MMP9 | |
| SCHEMBL4753430 | 0.92 | HTR1A (0.46) | HTR1AFOLR1PTPN1MMP2MMP9 | |
| SCHEMBL13100870 | 0.91 | HTR1A (0.48) | HTR1AFOLR1PTPN1MMP2MMP9 | |
| SCHEMBL4753277 | 0.91 | HTR1A (0.45) | HTR1AFOLR1PTPN1MMP2MMP9 | |
| SCHEMBL4753486 | 0.91 | HTR1A (0.41) | HTR1AFOLR1PTPN1PRMT1FOLH1 | |
| SCHEMBL4753273 | 0.90 | HTR1A (0.45) | HTR1AFOLR1PTPN1MMP2MMP9 | |
| SCHEMBL4753262 | 0.89 | HTR1A (0.44) | HTR1AFOLR1PTPN1MMP2MMP9 | |
| SCHEMBL4753316 | 0.89 | HTR1A (0.45) | HTR1AFOLR1PTPN1MMP2MMP9 | |
| SCHEMBL13100866 | 0.89 | HTR1A (0.47) | HTR1AFOLR1PTPN1MMP2MMP9 | |
| SCHEMBL13531857 | 0.89 | HTR1A (0.47) | HTR1AFOLR1PTPN1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8178282-B2 | Heat-sensitive imaging element | AGFA GRAPHICS NV (BE) | 2012-05-15 | — | — | US | disclosed |
| US-20100040976-A1 | HEAT-SENSITIVE IMAGING ELEMENT | AGFA GRAPHICS NV (BE) | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100040976-A1 | HEAT-SENSITIVE IMAGING ELEMENT | HEATR1, HEATR6, HSPA8 | HTR1A 1158/4885FOLR1 4305/4885PTPN1 4269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.