Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 4/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | LCAT | P04180 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAT2A | P31153 | 1/20 | 0.30 |
| ▸ | SCD | O00767 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13985521 | 1.00 | SPR (0.34) | SPRTDP1POLBAPEX1RECQL | |
| SCHEMBL4756546 | 0.83 | SPR (0.34) | SPRL3MBTL1MAPTCNR1 | |
| SCHEMBL13985526 | 0.83 | SPR (0.34) | SPRL3MBTL1MAPTCNR1 | |
| SCHEMBL4756541 | 0.83 | SPR (0.34) | SPRL3MBTL1MAPTCNR1 | |
| SCHEMBL13985500 | 0.81 | SPR (0.33) | SPR | |
| SCHEMBL4753494 | 0.81 | SPR (0.33) | SPR | |
| SCHEMBL4755215 | 0.77 | DRD1 (0.40) | POLBALDH1A1MEN1KMT2AHTT | |
| SCHEMBL4755594 | 0.77 | DRD1 (0.37) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL4755592 | 0.77 | DRD1 (0.37) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL4755213 | 0.77 | DRD1 (0.40) | POLBALDH1A1MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156607-A1 | SUBSTITUTED PYRIMIDINONES | NEUROGEN CORPORATION (US) | 2008-12-24 | — | — | WO | claimed |