Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 3/20 | 0.40 |
| ▸ | DRD5 | P21918 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAT2A | P31153 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4755215 | 1.00 | DRD1 (0.40) | DRD1DRD5MEN1KMT2AALDH1A1 | |
| SCHEMBL4755592 | 0.90 | DRD1 (0.37) | DRD1DRD5MEN1KMT2AALDH1A1 | |
| SCHEMBL4755594 | 0.90 | DRD1 (0.37) | DRD1DRD5MEN1KMT2AALDH1A1 | |
| SCHEMBL4755659 | 0.89 | MEN1 (0.39) | MEN1KMT2AALDH1A1SMN1; SMN2HCAR1 | |
| SCHEMBL4755656 | 0.89 | MEN1 (0.39) | MEN1KMT2AALDH1A1SMN1; SMN2HCAR1 | |
| SCHEMBL4753245 | 0.89 | DRD2 (0.41) | DRD1DRD5MEN1KMT2AALDH1A1 | |
| SCHEMBL4753244 | 0.89 | DRD2 (0.41) | DRD1DRD5MEN1KMT2AALDH1A1 | |
| SCHEMBL4755166 | 0.88 | AVPR1A (0.39) | DRD1DRD5KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL13985302 | 0.88 | TSHR (0.31) | DRD1DRD5HCAR1NR1H2NR1H3 | |
| SCHEMBL4755551 | 0.88 | MAPT (0.34) | MEN1KMT2AALDH1A1HCAR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156607-A1 | SUBSTITUTED PYRIMIDINONES | NEUROGEN CORPORATION (US) | 2008-12-24 | — | — | WO | claimed |