Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 2/20 | 0.37 |
| ▸ | DRD5 | P21918 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | APLNR | P35414 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAT2A | P31153 | 1/20 | 0.33 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4755594 | 1.00 | DRD1 (0.37) | DRD1DRD5ALDH1A1CYP1A2APLNR | |
| SCHEMBL4755659 | 0.92 | MEN1 (0.39) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL4755656 | 0.92 | MEN1 (0.39) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL4755551 | 0.91 | MAPT (0.34) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL13985302 | 0.91 | TSHR (0.31) | DRD1DRD5 | |
| SCHEMBL4755166 | 0.91 | AVPR1A (0.39) | DRD1DRD5ALDH1A1KMT2AHPGD | |
| SCHEMBL4755547 | 0.91 | MAPT (0.34) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL4755169 | 0.91 | AVPR1A (0.39) | DRD1DRD5ALDH1A1KMT2AHPGD | |
| SCHEMBL4755215 | 0.90 | DRD1 (0.40) | DRD1DRD5ALDH1A1MEN1KMT2A | |
| SCHEMBL4755213 | 0.90 | DRD1 (0.40) | DRD1DRD5ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156607-A1 | SUBSTITUTED PYRIMIDINONES | NEUROGEN CORPORATION (US) | 2008-12-24 | — | — | WO | claimed |