Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 2/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
| ▸ | PDE1A | P54750 | 1/20 | 0.30 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.30 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13985500 | 1.00 | SPR (0.33) | SPRAVPR1AMCHR1GRIN1GRIN2A | |
| SCHEMBL13985526 | 0.89 | SPR (0.34) | SPRPDE1APDE1BPDE1C | |
| SCHEMBL4756541 | 0.89 | SPR (0.34) | SPRPDE1APDE1BPDE1C | |
| SCHEMBL4756546 | 0.89 | SPR (0.34) | SPRPDE1APDE1BPDE1C | |
| SCHEMBL4755651 | 0.82 | SPR (0.32) | SPRAVPR1AAPLNRPDE1APDE1B | |
| SCHEMBL13985521 | 0.81 | SPR (0.34) | SPR | |
| SCHEMBL4753450 | 0.81 | SPR (0.34) | SPR | |
| SCHEMBL4753522 | 0.80 | SPR (0.32) | SPRAVPR1AGRIN1GRIN2AAPLNR | |
| SCHEMBL4755767 | 0.80 | CHRNB2 (0.34) | SPRAVPR1AMCHR1 | |
| SCHEMBL4755765 | 0.80 | CHRNB2 (0.34) | SPRAVPR1AMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156607-A1 | SUBSTITUTED PYRIMIDINONES | NEUROGEN CORPORATION (US) | 2008-12-24 | — | — | WO | claimed |
| WO-2008156607-A1 | SUBSTITUTED PYRIMIDINONES | NEUROGEN CORPORATION (US) | 2008-12-24 | — | — | WO | disclosed |