SCHEMBL4753460 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	RAB9A	P51151	4/20	0.38

▸	SMN1; SMN2	Q16637	3/20	0.38

▸	NPC1	O15118	2/20	0.38

▸	XDH	P47989	1/20	0.38

▸	MEN1	O00255	1/20	0.38

▸	KMT2A	Q03164	1/20	0.38

▸	MAPT	P10636	4/20	0.37

▸	MAPK1	P28482	2/20	0.37

▸	ALDH1A1	P00352	1/20	0.36

▸	BACE1	P56817	3/20	0.36

▸	TDP1	Q9NUW8	1/20	0.35

▸	CYP1B1	Q16678	1/20	0.34

▸	EGFR	P00533	1/20	0.34

▸	ERBB2	P04626	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL3024324	0.74	TDP1 (0.41)	RAB9ASMN1; SMN2NPC1MEN1KMT2A
SCHEMBL3018879	0.65	MEN1 (0.48)	RAB9ASMN1; SMN2NPC1MEN1KMT2A
SCHEMBL3130519	0.65	RAB9A (0.39)	RAB9ASMN1; SMN2MEN1KMT2AMAPT
SCHEMBL3013301	0.65	MAPT (0.48)	RAB9ASMN1; SMN2NPC1MEN1KMT2A
SCHEMBL3021835	0.64	KMT2A (0.42)	RAB9ASMN1; SMN2NPC1MEN1KMT2A
SCHEMBL6908269	0.62	KMT2A (0.63)	RAB9ANPC1MEN1KMT2AMAPT
SCHEMBL3256455	0.62	MEN1 (0.72)	RAB9ASMN1; SMN2NPC1MEN1KMT2A
SCHEMBL6908272	0.62	KMT2A (0.63)	RAB9ANPC1MEN1KMT2AMAPT
SCHEMBL6911280	0.61	KMT2A (0.57)	RAB9ASMN1; SMN2NPC1MEN1KMT2A
SCHEMBL6911282	0.61	KMT2A (0.57)	RAB9ASMN1; SMN2NPC1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2008144933-A1	CINNAMOYL INHIBITORS OF TRANSGLUTAMINASE	Université de Montréal (CA)	2008-12-04	—	—	WO	disclosed