Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | SNCA | P37840 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6908269 | 1.00 | KMT2A (0.63) | KMT2AMEN1ESR1ESR2MAPT | |
| SCHEMBL3794210 | 0.88 | MEN1 (0.56) | KMT2AMEN1ESR2MAPTLMNA | |
| SCHEMBL9745903 | 0.86 | RAB9A (0.48) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL6906382 | 0.85 | KMT2A (0.53) | KMT2AMEN1ESR1ESR2MAPT | |
| SCHEMBL6906384 | 0.85 | KMT2A (0.53) | KMT2AMEN1ESR1ESR2MAPT | |
| SCHEMBL3794214 | 0.85 | MEN1 (0.55) | KMT2AMEN1ESR2MAPTLMNA | |
| SCHEMBL3794216 | 0.85 | MEN1 (0.55) | KMT2AMEN1ESR2MAPTLMNA | |
| SCHEMBL11973532 | 0.82 | RAB9A (0.53) | KMT2AMEN1ESR2MAPTLMNA | |
| SCHEMBL11973525 | 0.82 | RAB9A (0.53) | KMT2AMEN1ESR2MAPTLMNA | |
| SCHEMBL28003594 | 0.80 | EPHX2 (0.60) | KMT2AMEN1MAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040092595-A1 | Analgesic agent | SEIWA PHARMACEUTICALS, LTD. (JP) | 2004-05-13 | — | — | US | disclosed |
| US-20030100516-A1 | Analgesic agent | SEIWA PHARMACEUTICALS, LTD. (JP) | 2003-05-29 | — | — | US | disclosed |
| EP-1118324-A1 | Analgesic agent comprising a cyclobutanedicarboxylic acid derivative | Seiwa Pharmaceutical, Limited (JP) | 2001-07-25 | — | — | EP | disclosed |
| US-4074046-A | REACTING NITROGENEOUS COMPOUND WITH CARBON MONOXIDE | AMERICAN CYANAMID COMPANY (US) | 1978-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092595-A1 | Analgesic agent | OPRD1, FPR1, OPRK1 | KMT2A 3322/4885MEN1 4851/4885ESR1 3976/4885 |
| US-20030100516-A1 | Analgesic agent | OPRD1, FPR1, OPRK1 | KMT2A 3322/4885MEN1 4851/4885ESR1 3976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.