Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.46 |
| ▸ | SCD | O00767 | 11/20 | 0.43 |
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4753766 | 0.92 | SCD5 (0.42) | SCD5SCDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1221577 | 0.83 | SCD5 (0.49) | SCD5SCDDCTPP1CYP2C9CYP2C19 | |
| SCHEMBL4753878 | 0.83 | CYP2C9 (0.47) | SCDDCTPP1CYP2C9CYP2C19HTR2B | |
| SCHEMBL4753472 | 0.76 | SCN5A (0.47) | SCDDCTPP1CYP2C9CYP2C19HTR2B | |
| SCHEMBL1222564 | 0.75 | SCD5 (0.44) | SCD5SCDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1222168 | 0.74 | SCD5 (0.54) | SCD5SCDDCTPP1NPC1RAB9A | |
| SCHEMBL4753470 | 0.71 | SCD (0.51) | SCDCYP2C9CYP2C19HTR2BMAPK14 | |
| Hydrochloric Acid SCHEMBL3466569 | 0.71 | SCD (0.50) | SCDCYP2C9CYP2C19HTR2BMAPK14 | |
| SCHEMBL221663 | 0.70 | POLB (0.47) | SCDCYP2C9CYP2C19HTR2BMAPK14 | |
| SCHEMBL1221562 | 0.68 | NPC1 (0.58) | SCD5SCDDCTPP1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008157844-A1 | NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-COA DESATURASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2008-12-24 | — | — | WO | disclosed |