Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29010947 | 0.86 | DHFR (0.59) | — | |
| SCHEMBL13123229 | 0.83 | KMT2A (0.44) | TDP1POLBMAPTKMT2AATM | |
| SCHEMBL13984040 | 0.82 | DHFR (0.53) | MAPTATM | |
| SCHEMBL27180283 | 0.79 | GRIN2D (0.51) | TDP1POLBMAPTKMT2A | |
| SCHEMBL6407119 | 0.79 | SMN1; SMN2 (0.48) | TDP1POLBMAPTKMT2A | |
| SCHEMBL4753250 | 0.79 | ALDH1A1 (0.56) | MAPTKMT2ADCPS | |
| SCHEMBL4755431 | 0.76 | HTT (0.44) | — | |
| SCHEMBL4755412 | 0.76 | DCPS (0.53) | DCPS | |
| Quinazoline-2,4,6-Triamine SCHEMBL30050079 | 0.75 | DCPS (0.57) | DCPS | |
| Quinazoline-2,4,6-Triamine SCHEMBL335027 | 0.75 | DCPS (0.57) | DCPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008152142-A1 | 2 -AMINOQUINAZOLINE DERIVATIVES AND THEIR THERAPEUTIC USES | SOFTCURE PHARMACEUTICALS AB (SE) | 2008-12-18 | — | — | WO | disclosed |
| WO-2008152142-A1 | 2 -AMINOQUINAZOLINE DERIVATIVES AND THEIR THERAPEUTIC USES | SOFTCURE PHARMACEUTICALS AB (SE) | 2008-12-18 | — | — | WO | disclosed |