Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.30 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.30 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751475 | 0.80 | CDK4 (0.32) | — | |
| SCHEMBL4754028 | 0.80 | — | — | |
| SCHEMBL4754879 | 0.74 | HTR6 (0.40) | PDE10AHSD17B10 | |
| SCHEMBL14030991 | 0.63 | HPGD (0.36) | CSNK2A1PIM1CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL1134996 | 0.60 | ALDH1A1 (0.33) | — | |
| SCHEMBL16539926 | 0.59 | DGAT1 (0.38) | PDE10AMAPT | |
| SCHEMBL14697559 | 0.59 | DGAT1 (0.38) | TSHRHSD17B10 | |
| SCHEMBL17509954 | 0.58 | TDP1 (0.41) | LMNAMAPTTSHRHSD17B10 | |
| SCHEMBL14905348 | 0.58 | EGFR (0.41) | PDE10A | |
| SCHEMBL10341293 | 0.57 | ALDH1A1 (0.32) | LMNAMAPTTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008144253-A1 | PROTEIN KINASE INHIBITORS AND METHODS FOR USING THEREOF | IRM LLC (BM) | 2008-11-27 | — | — | WO | disclosed |
| WO-2008144253-A1 | PROTEIN KINASE INHIBITORS AND METHODS FOR USING THEREOF | IRM LLC (BM) | 2008-11-27 | — | — | WO | disclosed |