Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22438726 | 0.79 | DCTPP1 (0.54) | HTR6KDM4ESMN1; SMN2ALDH1A1DCTPP1 | |
| SCHEMBL25297700 | 0.74 | NR3C1 (0.37) | HTR6KDM4EALDH1A1HTT | |
| SCHEMBL4753554 | 0.74 | PDE10A (0.32) | HSD17B10PDE10A | |
| SCHEMBL4751475 | 0.71 | CDK4 (0.32) | DCTPP1 | |
| SCHEMBL6821486 | 0.70 | CYP1A2 (0.46) | HSD17B10ALDH1A1PDE4BPDE10A | |
| SCHEMBL20163948 | 0.69 | HTR6 (0.33) | HTR6KDM4EPDE4B | |
| SCHEMBL31240613 | 0.69 | CDC7 (0.33) | KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL2039524 | 0.69 | CDC7 (0.33) | KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL18359503 | 0.67 | PIK3CD (0.46) | — | |
| SCHEMBL24615302 | 0.66 | MAPT (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008144253-A1 | PROTEIN KINASE INHIBITORS AND METHODS FOR USING THEREOF | IRM LLC (BM) | 2008-11-27 | — | — | WO | disclosed |
| WO-2008144253-A1 | PROTEIN KINASE INHIBITORS AND METHODS FOR USING THEREOF | IRM LLC (BM) | 2008-11-27 | — | — | WO | disclosed |