Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 1/20 | 0.45 |
| ▸ | FEN1 | P39748 | 1/20 | 0.45 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4749731 | 0.99 | ERCC1 (0.44) | ERCC1FEN1ERCC4SMN1; SMN2KDM4E | |
| SCHEMBL4750309 | 0.99 | ERCC1 (0.44) | ERCC1FEN1ERCC4SMN1; SMN2KDM4E | |
| SCHEMBL7987871 | 0.88 | RAB9A (0.43) | KDM4EALDH1A1HPGDHSD17B10ADORA3 | |
| SCHEMBL8963574 | 0.80 | PDE2A (0.42) | SMN1; SMN2KDM4EALDH1A1HPGDADORA3 | |
| SCHEMBL28582957 | 0.76 | ERCC1 (0.68) | ERCC1FEN1ERCC4SMN1; SMN2KDM4E | |
| SCHEMBL7991847 | 0.75 | ADORA1 (0.47) | KDM4EALDH1A1HPGDADORA3ADORA1 | |
| SCHEMBL4753462 | 0.74 | CYP2D6 (0.40) | SMN1; SMN2ALDH1A1HSD17B10ADORA3ADORA2A | |
| SCHEMBL28916010 | 0.74 | ERCC1 (0.64) | ERCC1FEN1ERCC4SMN1; SMN2KDM4E | |
| SCHEMBL9517058 | 0.73 | RAF1 (0.62) | SMN1; SMN2KDM4EHPGDADORA3ADORA1 | |
| SCHEMBL9514583 | 0.72 | RAF1 (0.64) | ADORA3ADORA1ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008139941-A1 | SUBSTITUTED IMIDAZOLE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-20 | — | — | WO | disclosed |