Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.43 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987871 | 0.86 | RAB9A (0.43) | ADORA1NPC1RAB9AMAPK13RAF1 | |
| SCHEMBL7995205 | 0.77 | RAB9A (0.49) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL4750309 | 0.77 | ERCC1 (0.44) | ADORA1CYP2D6CYP2C9ADORA3ADORA2A | |
| SCHEMBL4749731 | 0.77 | ERCC1 (0.44) | ADORA1CYP2D6CYP2C9ADORA3ADORA2A | |
| SCHEMBL4753564 | 0.75 | ERCC1 (0.45) | ADORA1ADORA3ADORA2AALDH1A1HPGD | |
| SCHEMBL7977822 | 0.75 | KDM4E (0.47) | RAB9AMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL8963574 | 0.72 | PDE2A (0.42) | ADORA1MAPK14ADORA3ADORA2AKMT2A | |
| SCHEMBL20376630 | 0.72 | KDM4E (0.47) | RAB9AMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL7995189 | 0.71 | KDM4E (0.43) | RAB9AMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL7978027 | 0.71 | KDM4E (0.67) | MAPK14MEN1KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |