Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4750309 | 0.89 | ERCC1 (0.44) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| SCHEMBL4749731 | 0.89 | ERCC1 (0.44) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| SCHEMBL4753564 | 0.88 | ERCC1 (0.45) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| SCHEMBL7991847 | 0.86 | ADORA1 (0.47) | RAB9ANPC1ALDH1A1HPGDKDM4E | |
| SCHEMBL7995205 | 0.79 | RAB9A (0.49) | RAB9ANPC1ALDH1A1KDM4EMAPT | |
| SCHEMBL7995185 | 0.77 | ALDH1A1 (0.51) | RAB9ANPC1ALDH1A1HPGDNPSR1 | |
| SCHEMBL13748237 | 0.76 | NPSR1 (0.45) | NPC1ALDH1A1NPSR1MAPTKMT2A | |
| SCHEMBL4753462 | 0.75 | CYP2D6 (0.40) | RAB9ANPC1ALDH1A1NPSR1HSD17B10 | |
| SCHEMBL14273511 | 0.74 | SCN10A (0.41) | CYP2D6CYP2C9 | |
| SCHEMBL7989981 | 0.73 | ALDH1A1 (0.47) | RAB9ANPC1ALDH1A1HPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |