Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 2/20 | 0.40 |
| ▸ | HTR1B | P28222 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4297012 | 0.78 | MEN1 (0.46) | ALDH1A1SMN1; SMN2HPGDGAAKMT2A | |
| SCHEMBL4298262 | 0.78 | ALDH1A1 (0.45) | ALDH1A1GAAKMT2AL3MBTL1ABHD6 | |
| SCHEMBL4752576 | 0.78 | KMT2A (0.43) | ALDH1A1GAAKMT2ATDP1ABHD6 | |
| SCHEMBL4752095 | 0.77 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2HPGDGAAALOX15 | |
| SCHEMBL4752523 | 0.77 | ABHD6 (0.43) | ALDH1A1SMN1; SMN2GAAKMT2AL3MBTL1 | |
| SCHEMBL4752093 | 0.77 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2HPGDKMT2AL3MBTL1 | |
| SCHEMBL10795224 | 0.76 | HPGD (0.37) | ALDH1A1SMN1; SMN2HPGDGAAKMT2A | |
| SCHEMBL10790280 | 0.76 | HPGD (0.40) | ALDH1A1SMN1; SMN2HPGDGAAKMT2A | |
| SCHEMBL4749712 | 0.75 | RAB9A (0.46) | ALDH1A1SMN1; SMN2KMT2AL3MBTL1MGLL | |
| SCHEMBL4752657 | 0.74 | SMN1; SMN2 (0.50) | ALDH1A1SMN1; SMN2HPGDGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008139941-A1 | SUBSTITUTED IMIDAZOLE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-20 | — | — | WO | disclosed |